Management of Cushing’s syndrome: Chair Interview
John Newell-Price (UK)
E Floor, The Medical School
University of Sheffield
Beech Hill Road
John Newell-Price did his specialist training in endocrinology at St. Bartholomew’s Hospital, London, where he was an MRC Training Fellow from 1995-1998. He was appointed Senior Lecturer and Honorary Consultant Physician at the University of Sheffield in 2000 where the focus of both his clinical and basic research has been on glucocorticoids. His group has identified important aspects of epigenetic regulation of proopiomelanocortin, the key regulator of the hypothalamic-pituitary-adrenal axis, and now is using this information to design strategies to modify over-expression in conditions of excess hormone secretion, such as Cushing’s disease. The clinical research programme has been investigating means of inhibiting excess ACTH in man and improving cortisol replacement in adrenally insufficient patients. Other work focuses on the diagnostic and management strategies for patients with Cushing’s syndrome, and those also for patients with neuroendocrine tumours.